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article-journal
p16INK4a Regulates Cellular Senescence in PD-1-Expressing Human T Cells
T-cell dysfunction arising upon repeated antigen exposure prevents effective immunity and immunotherapy. Using various clinically and …
Valérie Janelle
,
Mathieu Neault
,
Marie-Ève Lebel
,
Maurice Dave Sousa De
,
Salix Boulet
,
Ludovic Durrieu
,
Cédric Carli
,
Chloé Muzac
,
Sébastien Lemieux
,
Nathalie Labrecque
,
J. Heather Melichar
,
A. Frédérick Mallette
,
Jean-Sébastien Delisle
Cite
UM171-Expanded Cord Blood Transplants Support Robust T Cell Reconstitution with Low Rates of Severe Infections
Rapid T cell reconstitution following hematopoietic stem cell transplantation (HSCT) is essential for protection against infections and …
Maude Dumont-Lagacé
,
Qi Li
,
Mégane Tanguay
,
Jalila Chagraoui
,
Tibila Kientega
,
B. Guillaume Cardin
,
Ann Brasey
,
Assya Trofimov
,
Cédric Carli
,
Imran Ahmad
,
M. Nadia Bambace
,
Léa Bernard
,
L. Thomas Kiss
,
Jean Roy
,
Denis-Claude Roy
,
Sébastien Lemieux
,
Claude Perreault
,
Francis Rodier
,
Frédéric Simon Dufresne
,
Lambert Busque
,
Silvy Lachance
,
Guy Sauvageau
,
Sandra Cohen
,
Jean-Sébastien Delisle
Cite
DOI
Factorized embeddings learns rich and biologically meaningful embedding spaces using factorized tensor decomposition
The recent development of sequencing technologies revolutionized our understanding of the inner workings of the cell as well as the way …
Assya Trofimov
,
Paul Joseph Cohen
,
Yoshua Bengio
,
Claude Perreault
,
Sébastien Lemieux
Cite
DOI
Genetic characterization of ABT-199 sensitivity in human AML
Acute myeloid leukemias (AML) with mutations in the NPM1 gene (NPM1c+) represent a large AML subgroup with varying response to …
Richard Bisaillon
,
Céline Moison
,
Clarisse Thiollier
,
Jana Krosl
,
Marie-Eve Bordeleau
,
Bernhard Lehnertz
,
Vincent-Philippe Lavallée
,
Tara MacRae
,
Nadine Mayotte
,
Caroline Labelle
,
Geneviève Boucher
,
Jean-Francois Spinella
,
Isabel Boivin
,
Giovanni D’Angelo
,
Sylvie Lavallée
,
Anne Marinier
,
Sébastien Lemieux
,
Josée Hébert
,
Guy Sauvageau
Cite
DOI
Hematopoietic stem cell transplantation using single UM171-expanded cord blood - a single-arm phase 1–2 safety and feasibility study
Sandra Cohen
,
Jean Roy
,
Silvy Lachance
,
Jean-Sébastien Delisle
,
Anne Marinier
,
Lambert Busque
,
Denis-Claude Roy
,
Frederic Barabe
,
Imran Ahmad
,
Nadia Bambace
,
Léa Bernard
,
Thomas Kiss
,
Philippe Bouchard
,
Pierre Caudrelier
,
Sévérine Landais
,
Fannie Larochelle
,
Jalila Chagraoui
,
Bernhard Lehnertz
,
Sophie Corneau
,
Elisa Tomellini
,
van A. J. Jeroen Kampen
,
J. Jan Cornelissen
,
Maude Dumont-Lagacé
,
Mégane Tanguay
,
Qi Li
,
Sébastien Lemieux
,
W. Peter Zandstra
,
Guy Sauvageau
Cite
DOI
High frequency of germline RUNX1 mutations in patients with RUNX1-mutated AML
RUNX1 is mutated in ∼10% of adult acute myeloid leukemia (AML). Although most RUNX1 mutations in this disease are believed to be …
Laura Simon
,
Jean-Francois Spinella
,
Chi-Yuan Yao
,
Vincent-Philippe Lavallée
,
Isabel Boivin
,
Geneviève Boucher
,
Éric Audemard
,
Marie-Eve Bordeleau
,
Sébastien Lemieux
,
Josée Hébert
,
Guy Sauvageau
Cite
DOI
MAPDP - A Cloud-Based Computational Platform for Immunopeptidomics Analyses
The immunopeptidome corresponds to the repertoire of peptides presented at the cell surface by the major histocompatibility complex …
Mathieu Courcelles
,
Chantal Durette
,
Tariq Daouda
,
Jean-Philippe Laverdure
,
Krystel Vincent
,
Sébastien Lemieux
,
Claude Perreault
,
Pierre Thibault
Cite
DOI
Proteogenomics Uncovers a Vast Repertoire of Shared Tumor-Specific Antigens in Ovarian Cancer
High-grade serous ovarian cancer (HGSC), the principal cause of death from gynecologic malignancies in the world, has not significantly …
Qingchuan Zhao
,
Jean-Philippe Laverdure
,
Joël Lanoix
,
Chantal Durette
,
Caroline Côté
,
Éric Bonneil
,
M. Céline Laumont
,
Patrick Gendron
,
Krystel Vincent
,
Mathieu Courcelles
,
Sébastien Lemieux
,
G. Douglas Millar
,
S. Pamela Ohashi
,
Pierre Thibault
,
Claude Perreault
Cite
DOI
Qualitative Changes in Cortical Thymic Epithelial Cells Drive Postpartum Thymic Regeneration
During gestation, sex hormones cause a significant thymic involution which enhances fertility. This thymic involution is rapidly …
Maude Dumont-Lagacé
,
Tariq Daouda
,
Lucyle Depoërs
,
Jérémie Zumer
,
Yahya Benslimane
,
Sylvie Brochu
,
Lea Harrington
,
Sébastien Lemieux
,
Claude Perreault
Cite
STRIPAK regulates Slik localization to control mitotic morphogenesis and epithelial integrity
Proteins of the ezrin, radixin, and moesin (ERM) family control cell and tissue morphogenesis. We previously reported that moesin, the …
Valérie Camille Jamblinne De
,
Barbara Decelle
,
Mehrnoush Dehghani
,
Mathieu Joseph
,
Neera Sriskandarajah
,
Kévin Leguay
,
Basile Rambaud
,
Sébastien Lemieux
,
P. Philippe Roux
,
R. David Hipfner
,
Sébastien Carréno
Cite
DOI
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