Guy Sauvageau

Latest

• Identification of Acute Myeloid Leukemia Cell Surface Therapeutic Targets Using Single Cell RNA Sequencing Supported By Surface Proteomics
• Identification of Novel Cell Surface Therapeutic Targets for KMT2A-Rearranged Acute Myeloid Leukemia
• IL1R1 Expression Predicts the Benefit from Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Acute Myeloid Leukemia and Intermediate-Risk Cytogenetics
• Targeting PLZF Enhances Glucocorticoid Sensitivity in Acute Myeloid Leukemia
• Baseline Acute Myeloid Leukemia Prognosis Models using Transcriptomic and Clinical Profiles by Studying the Impacts of Dimensionality Reductions and Gene Signatures on Cox-Proportional Hazard
• ECTmatch - Optimizing Small-Scale Cord Blood Banking Through HLA Analysis
• Vesicular trafficking is a key determinant of the statin response in acute myeloid leukemia
• Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes
• Legal and Ethical Considerations for the Design and Use of Web Portals for Researchers Clinicians and Patients - Scoping Literature Review
• UM171-Expanded Cord Blood Transplants Support Robust T Cell Reconstitution with Low Rates of Severe Infections
• Exploring glucocorticoid sensitivity modulators in human acute myeloid leukemia
• Genetic characterization of ABT-199 sensitivity in human AML
• Hematopoietic stem cell transplantation using single UM171-expanded cord blood - a single-arm phase 1–2 safety and feasibility study
• High frequency of germline RUNX1 mutations in patients with RUNX1-mutated AML
• Single UM171-Expanded Cord Blood Transplants Support Robust T-Cell Reconstitution with Low Rates of Severe Infections
• Surface proteomics reveals novel potentiel AML antigens for immunitherapeutic targeting
• Complex karyotype AML displays G2/M signature and hypersensitivity to PLK1 inhibition
• Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A NPM1 and FLT3-ITD triple-mutated AML
• Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia
• Targeted variant detection using unaligned RNA-Seq reads
• Targeted variant detection using unaligned RNA-Seq reads
• Chemogenomic Approach Unveils the Increased Susceptibility of RUNX1-Mutated AML to Glucocorticoids
• Chemogenomic Profiling of Complex Karyotype AML Reveals a Novel Susceptibility to G2/M Checkpoint Inhibition Mediated By HMGA2 Overexpression
• High expression of HMGA2 independently predicts poor clinical outcomes in acute myeloid leukemia
• Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of Mitochondrial Vulnerability in Acute Myeloid Leukemia
• Single UM171 Expanded Cord Blood Permits Transplantation of Better HLA Matched Cords with Excellent Gvhd Relapse Free Survival
• Target variant detection in leukemia using unaligned RNA-Seq reads
• Transcriptomic landscape of acute promyelocytic leukemia reveals aberrant surface expression of the platelet aggregation agonist Podoplanin