Bioinformatics & Cancer Research

Our lab is affiliated to the Institute for Research in Immunology and Cancer (IRIC) at the Université de Montréal (UdeM). Our multidisciplinary team develops bioinformatics tools and analysis pipelines, and leverages machine learning and other computational approaches to analyze omics data such as transcriptomic, chemogenomic, and proteomic data. Through fundamental, translational and clinical research, we help improve cancer treatment.

What’s new

Two types of human TCR differentially regulate reactivity to self and non-self antigens
Two types of human TCR differentially regulate reactivity to self and non-self antigens

A new bioinformatics analysis of TCR sequences by Assya Trofimov reveals two main classes of functionally distinct TCRs. Her paper, in collaboration with researchers from Claude Perreault’s lab, is available on the BioRXiv preprint server following this link.

Leonard Sauve's poster accepted at RECOMB 2022
Leonard Sauve's poster accepted at RECOMB 2022

A new poster by Leonard Sauve has been accepted for presentation at the 26th annual international conference on research in computational molecular biology, aka RECOMB 2022. The presentation, titled “Impact of Dimensionality REduction Parameters for Cox Proportional-Hazards Applied to Cancer Gene Expression”, will be made available at a later time. The poster acceptation notice may be viewed on the RECOMB 2022 website under Program > Accepted Posters. The RECOMB 2022 conference begins May 22 and ends May 25 in La Jolla, California, USA.

Assya Trofimov Awarded Mahan Postdoc Fellowship
Assya Trofimov Awarded Mahan Postdoc Fellowship

Congratulations to Assya Trofimov for winning the Mahan post-doc fellowship. The contest for this prestigious fellowship is held annually by the Fred Hutchison Cancer Research Center in Seattle to reward exceptional candidates by offering financial support for 21 months for computatinoal biology research projects.

Good news for Maria Virginia Ruiz Cueva!
Good news for Maria Virginia Ruiz Cueva!

Maria Virginia Ruiz Cuevas has been accepted to present a poster about her paper Most non-canonical proteins uniquely populate the proteome or immunopeptidome at the RECOMB 2021 conference (August 29 – September 1, 2021).