Vincent-Philippe Lavallée

Récents

• Identification of Acute Myeloid Leukemia Cell Surface Therapeutic Targets Using Single Cell RNA Sequencing Supported By Surface Proteomics
• Identification of Novel Cell Surface Therapeutic Targets for KMT2A-Rearranged Acute Myeloid Leukemia
• IL1R1 Expression Predicts the Benefit from Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Acute Myeloid Leukemia and Intermediate-Risk Cytogenetics
• Vesicular trafficking is a key determinant of the statin response in acute myeloid leukemia
• Genetic characterization of ABT-199 sensitivity in human AML
• High frequency of germline RUNX1 mutations in patients with RUNX1-mutated AML
• Surface proteomics reveals novel potentiel AML antigens for immunitherapeutic targeting
• Complex karyotype AML displays G2/M signature and hypersensitivity to PLK1 inhibition
• Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A NPM1 and FLT3-ITD triple-mutated AML
• Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia
• Targeted variant detection using unaligned RNA-Seq reads
• Chemogenomic Approach Unveils the Increased Susceptibility of RUNX1-Mutated AML to Glucocorticoids
• Chemogenomic Profiling of Complex Karyotype AML Reveals a Novel Susceptibility to G2/M Checkpoint Inhibition Mediated By HMGA2 Overexpression
• High expression of HMGA2 independently predicts poor clinical outcomes in acute myeloid leukemia
• Target variant detection in leukemia using unaligned RNA-Seq reads
• Transcriptomic landscape of acute promyelocytic leukemia reveals aberrant surface expression of the platelet aggregation agonist Podoplanin