J. P. Laverdure

Latest

• Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes
• MAPDP: A Cloud-Based Computational Platform for Immunopeptidomics Analyses
• Proteogenomics Uncovers a Vast Repertoire of Shared Tumor-Specific Antigens in Ovarian Cancer
• Widespread and tissue-specific expression of endogenous retroelements in human somatic tissues
• Noncoding regions are the main source of targetable tumor-specific antigens
• Detection of Quiescent Radioresistant Epithelial Progenitors in the Adult Thymus
• Global proteogenomic analysis of human MHC class I-associated peptides derived from non-canonical reading frames
• MHC class I-associated peptides derive from selective regions of the human genome
• Proteogenomic-based discovery of minor histocompatibility antigens with suitable features for immunotherapy of hematologic cancers
• MHC I-associated peptides preferentially derive from transcripts bearing miRNA response elements
• The MHC I immunopeptidome conveys to the cell surface an integrative view of cellular regulation