J. Krosl

Latest

• Vesicular trafficking is a key determinant of the statin response in acute myeloid leukemia
• Genetic characterization of ABT-199 sensitivity in human AML
• Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia
• Transcriptomic landscape of acute promyelocytic leukemia reveals aberrant surface expression of the platelet aggregation agonist Podoplanin
• A novel approach for the identification of efficient combination therapies in primary human acute myeloid leukemia specimens
• Chemogenomic Landscape of RUNX1-mutated AML Reveals Importance of RUNX1 Allele Dosage in Genetics and Glucocorticoid Sensitivity
• Chemo-genomic interrogation of CEBPA mutated AML reveals recurrent CSF3R mutations and subgroup sensitivity to JAK inhibitors
• GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo
• The transcriptomic landscape and directed chemical interrogation of MLL-rearranged acute myeloid leukemias
• Identification of small molecules that support human leukemia stem cell activity ex vivo
• A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia