I. Boivin

Latest

• Vesicular trafficking is a key determinant of the statin response in acute myeloid leukemia
• Genetic characterization of ABT-199 sensitivity in human AML
• High frequency of germline RUNX1 mutations in patients with RUNX1-mutated AML
• Complex karyotype AML displays G2/M signature and hypersensitivity to PLK1 inhibition
• Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia
• A novel approach for the identification of efficient combination therapies in primary human acute myeloid leukemia specimens
• Chemo-genomic interrogation of CEBPA mutated AML reveals recurrent CSF3R mutations and subgroup sensitivity to JAK inhibitors
• GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo
• Identification of MYC mutations in acute myeloid leukemias with NUP98-NSD1 translocations
• RNA-sequencing analysis of core binding factor AML identifies recurrent ZBTB7A mutations and defines RUNX1-CBFA2T3 fusion signature