D. P. Granados

Latest

• Global proteogenomic analysis of human MHC class I-associated peptides derived from non-canonical reading frames
• MHC class I-associated peptides derive from selective regions of the human genome
• Proteogenomic-based discovery of minor histocompatibility antigens with suitable features for immunotherapy of hematologic cancers
• Impact of genomic polymorphisms on the repertoire of human MHC class I-associated peptides
• MHC I-associated peptides preferentially derive from transcripts bearing miRNA response elements
• Deletion of immunoproteasome subunits imprints on the transcriptome and has a broad impact on peptides presented by major histocompatibility complex I molecules