C. Pabst

Latest

• Vesicular trafficking is a key determinant of the statin response in acute myeloid leukemia
• Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A, NPM1, and FLT3-ITD triple-mutated AML
• Transcriptomic landscape of acute promyelocytic leukemia reveals aberrant surface expression of the platelet aggregation agonist Podoplanin
• Chemo-genomic interrogation of CEBPA mutated AML reveals recurrent CSF3R mutations and subgroup sensitivity to JAK inhibitors
• GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo
• Transcriptome analysis of G protein-coupled receptors in distinct genetic subgroups of acute myeloid leukemia: identification of potential disease-specific targets
• Identification of small molecules that support human leukemia stem cell activity ex vivo