C. Cote

Latest

• Most non-canonical proteins uniquely populate the proteome or immunopeptidome
• Proteogenomics Uncovers a Vast Repertoire of Shared Tumor-Specific Antigens in Ovarian Cancer
• Widespread and tissue-specific expression of endogenous retroelements in human somatic tissues
• Noncoding regions are the main source of targetable tumor-specific antigens
• MHC class I-associated peptides derive from selective regions of the human genome
• Proteogenomic-based discovery of minor histocompatibility antigens with suitable features for immunotherapy of hematologic cancers
• Impact of genomic polymorphisms on the repertoire of human MHC class I-associated peptides
• MHC I-associated peptides preferentially derive from transcripts bearing miRNA response elements