P. Thibault

Récents

• Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes
• CAMAP: Artificial neural networks unveil the role of codon arrangement in modulating MHC-I peptides presentation
• Most non-canonical proteins uniquely populate the proteome or immunopeptidome
• MAPDP: A Cloud-Based Computational Platform for Immunopeptidomics Analyses
• Proteogenomics Uncovers a Vast Repertoire of Shared Tumor-Specific Antigens in Ovarian Cancer
• Widespread and tissue-specific expression of endogenous retroelements in human somatic tissues
• Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia
• Noncoding regions are the main source of targetable tumor-specific antigens
• Global proteogenomic analysis of human MHC class I-associated peptides derived from non-canonical reading frames
• MHC class I-associated peptides derive from selective regions of the human genome
• Proteogenomic-based discovery of minor histocompatibility antigens with suitable features for immunotherapy of hematologic cancers
• Impact of genomic polymorphisms on the repertoire of human MHC class I-associated peptides
• Phosphoproteome dynamics reveal novel ERK1/2 MAP kinase substrates with broad spectrum of functions
• MHC I-associated peptides preferentially derive from transcripts bearing miRNA response elements
• Occurrence and detection of phosphopeptide isomers in large-scale phosphoproteomics experiments
• ProteoConnections: a bioinformatics platform to facilitate proteome and phosphoproteome analyses
• The MHC I immunopeptidome conveys to the cell surface an integrative view of cellular regulation
• Deletion of immunoproteasome subunits imprints on the transcriptome and has a broad impact on peptides presented by major histocompatibility complex I molecules
• The phagosomal proteome in interferon-gamma-activated macrophages
• The MHC class I peptide repertoire is molded by the transcriptome